Analisis C-Type Lectin

  • Iman Supriatna Politeknik Kelautan dan Perikanan Sorong


This study aimed to determine the diversity of c-type lectin on the various groups of species based on data contained in National Center for Biotechnology Information (NCBI). The method used is a bioinformatics study by analyzing the amino acid molecules lectin particular type of c-type lectin found in NCBI and analyze of sequence and scores of c-type lectin with Prosite analysis based. The results showed that the data of genbank seen as the varying length of the amino acid sequence types of c-type lectin of groups of species of fish 159-304 aa, bivalves 155-524 aa, plants 349-414 aa, fungi 593-981 aa, and bacteria 564-4379 aa. Prosite analysis results with the c-type lectin on some species have slightly varied score that O. niloticus 18.010, M. meretrik 18, 112, A. thaliana and P. marinus 15,104. Potential C-type lectin on some of these species need to be analyzed further to determine the extraction technique and its benefits in the field of maritime affairs and fisheries.


Anderson, D.P. 2004. Immunostimulants, Vaccines, and Environmental Stressors in Aquaculture: NBT Assays to show Neutrophil Activity by these Immunomodulators. In: Cruz Suárez, L.E., Ricque Marie, D., Nieto López, M.G., Villarreal, D., Scholz, U. y González, M. 2004. Avances en Nutrición Acuícola VII. Memorias del VII Simposium Internacional de Nutrición Acuícola. 16-19 Noviembre, 2004. Hermosillo, Sonora, México.
Chuannan, X., L. Wei, B. Xuefang, D. Yuguang. 2005. Application of Lectins as Immunostimulants in Mariculture of Sea Cucumber Stichopus Japonicus. Available online at > 14/01/2014.
Drickamer, K. and M.E. Taylor. 1993. Structural Requirements for High Affinity Binding of Complex Ligands by the Macrophage Mannose Receptor. The Journal Of Biological Chemistry by The American Society for Biochemistry and Molecular Biology, Inc. Vol. 268, No. 1, pp. 399404,1993 Printed in U.S.A. Page 399-404.
Luo, T., X. Zhang, Z. Shao, X. Xu. 2003. PmAV, a novel gene involved in virus resistance of shrimp Penaeus monodon. FEBS Lett. 11; 551(1-3):53-7.
Ma, T.H.T, S.H.K. Tiu, J.G. He, S.M. Chan. 2007. Molecular cloning of a C-type lectin (LvLT) from the shrimp Litopenaeus vannamei: Early gene down-regulationafter WSSV infection. Fish & Shellfish Immunology 23 pp 430-437.
Kong, H.J., E.M. Park, B.H. Nam , Y.O. Kim, W.J. Kim, H.J. Park, C.H. Lee, S.J. Lee. 2008. A C-type lectin like-domain (CTLD)-containing protein (PtLP) from the swimming crab Portunus trituberculatus. Short Communication. Fish & Shellfish Immunology 25, 311-314.
Martínez, F.S. 2007. The Immune System Of Shrimp. Boletines Nicovita. 6 p
NCBI, 2015. diakses Juni 2015.
Parenrengi, A., Alimuddin, Sukenda, K. Sumantadinata, A. Tenriulo. 2009. Karakteristik Sekuen cDNA Pengkode Gen Anti Virus dari Udang Windu, Penaeus monodon. Jurnal Riset Akuakultur. Vol 4 No. Hal 1-13.
Samtleben, R., T. Hajto, K. H. And H. Wagner. 1999. Mistletoe Lectins As Immunostimulants (Chemistry, Pharmacology And Clinic). Immunomodulatory Agents from Plants. edited by H. Wagner © 1999 Birkhauser Verlag Basel/Switzerland. Page 223-241
Sharon, N., and H. Lis. 2004. Review : History of Lectins : From Hemagglutinins to Biological Recognition Molecules. Glicobiology. Vol. : 14, No. 11, Pages : 53-62. Oxford University. Downloaded from by guest on January 10, 2014
Sulasi, F., R. E. P. Mangindaan, F. Losung. 2013. Lektin Dari Spons Cliona varians Asal Perairan Malalayang Manado. Jurnal Pesisir dan Laut Tropis Volume 2 Nomor 1. Universitas Sam Ratulangi. Manado. Hal. 28-34.
Wei, X., X. Liu, J. Yang, J. Fang, H. Qiao, Y. Zhang, J. Yang. 2012. Two C-type lectins from shrimp Litopenaeus vannamei that might be involved in immune response against bacteria and virus. Fish & Shellfish Immunology 32 : 132-140.
How to Cite
Supriatna, I. (2015). Analisis C-Type Lectin. Jurnal Airaha, 4(1), 01 - 05. Retrieved from